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Article

Sirtuin 1 rs1467568 and rs7895833 in South African Indians with early-onset coronary artery disease.

Cardiovascular journal of Africa - 1 Jan 2000

Ramkaran Prithiksha, Phulukdaree Alisa, Khan Sajidah, Moodley Devapregasan, Chuturgoon Anil A

Abstract excerpt

BACKGROUND: Sirtuin 1 (SIRT1), a class III histone deacetylase, has been identified as a candidate molecule affecting the epigenetic mechanisms of cardiovascular disease (CVD). Previous studies have shown that some SIRT1 single-nucleotide polymorphisms (SNPs) are associated with body mass index, diabetes, blood pressure, cholesterol metabolism and coronary artery calcification. We investigated two A>G SIRT1 SNPs,...

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Identifiers

PMID: 27841908
DOI: 10.5830/CVJA-2015-085
PMCID: PMC5340890

Genes

CAD
SIRT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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