Article
Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus.
Journal of diabetes research - 1 Jan 2022
Wang Yuxin, Tong Linchao, Gu Nan, Ma Xiaowei, Lu Difei, Yu Dahong, Yu Na, Zhang Junqing, Li Jianping, Guo Xiaohui
Abstract excerpt
Aims: To explore the associations between polymorphisms in SIRT1 and coronary heart disease (CHD) risk in Chinese Han patients with type 2 diabetes (T2D). Methods: This case-controlled study enrolled 492 patients with T2D: 297 with CHD and 195 without CHD. Five SIRT1 haplotype-tagging single-nucleotide polymorphisms (rs3818291, rs12242965, rs3818292, rs4746720, and rs16924934) were selected from Chinese Han data...
