Article
Clinicopathological Manifestations and Immune Phenotypes in Adult-Onset Immunodeficiency with Anti-interferon-γ Autoantibodies.
Journal of clinical immunology - 1 Apr 2022
Chen Yi-Chun, Weng Shao-Wen, Ding Jing-Ya, Lee Chen-Hsiang, Ku Cheng-Lung, Huang Wen-Chi, You Huey-Ling, Huang Wan-Ting
Abstract excerpt
PURPOSE: Anti-interferon (IFN)-γ autoantibodies (anti-IFN-γ Abs) is an emerging adult-onset immunodeficiency syndrome. Immune dysfunction in this distinct disorder remains to be clarified. METHODS: We prospectively collected blood samples of 20 patients with anti-IFN-γ Abs and 40 healthy normal subjects. The percentages of lymphocyte subpopulations, most relevant to T, B, and NK cells, and the percentages of...
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