Article
Emerging clinical phenotypes associated with anti-cytokine autoantibodies.
Autoimmunity reviews - 1 Jun 2015
Vincent Thierry, Plawecki Maëlle, Goulabchand Radjiv, Guilpain Philippe, Eliaou Jean François
Abstract excerpt
Anti-cytokine autoantibodies (AAbs) are frequent and involve a very large panel of cytokines both in healthy subjects and in patients with various pathological conditions. In healthy individuals, anti-cytokine AAbs are described as a part of the natural AAb repertoire and are thought to contribute to the fine regulation of cytokine homeostasis. In some patients, neutralizing AAbs targeting cytokines required for...
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