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Article

Defects in the interferon-gamma and interleukin-12 pathways.

Immunological reviews - 1 Feb 2005

Rosenzweig Sergio D, Holland Steven M

Abstract excerpt

The interferon-gamma (IFN-gamma)/interleukin-12 (IL-12) pathway is a pivotal player in the immune system and is central to controlling mycobacterial infections. We highlight the most recent and relevant advances in understanding this pathway and their repercussions on basic and clinical science. Human mutations in IFN-gamma receptor-1 (IFN-gammaR1), IFN-gammaR2, IL-12p40, IL-12 receptor-beta1, signal transducer...

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Source

Identifiers

PMID: 15661020
DOI: 10.1111/j.0105-2896.2005.00227.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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