Article
Detection of Gag C-terminal mutations among HIV-1 non-B subtypes in a subset of Cameroonian patients.
Scientific reports - 26 Jan 2022
Teto Georges, Nka Alex Durand, Fokam Joseph, Bouba Yagai, Takou Désiré, Fabeni Lavinia, Carioti Luca, Armenia Daniele, Semengue Ezéchiel Ngoufack Jagni, Dambaya Béatrice, Sosso Samuel Martin, Colizzi Vittorio, Perno Carlo-Federico, Ceccherini-Silberstein Francesca, Santoro Maria Mercedes, Ndjolo Alexis
Abstract excerpt
Response to ritonavir-boosted-protease inhibitors (PI/r)-based regimen is associated with some Gag mutations among HIV-1 B-clade. There is limited data on Gag mutations and their covariation with mutations in protease among HIV-1 non-B-clades at PI/r-based treatment failure. Thus, we characterized Gag mutations present in isolates from HIV-1 infected individuals treated with a PI/r-regimen (n = 143) and compared...
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