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Gag P2/NC and pol genetic diversity, polymorphism, and drug resistance mutations in HIV-1 CRF02_AG- and non-CRF02_AG-infected patients in Yaoundé, Cameroon.

Scientific reports - 26 Oct 2017

Teto Georges, Tagny Claude T, Mbanya Dora, Fonsah Julius Y, Fokam Joseph, Nchindap Emilienne, Kenmogne Léopoldine, Njamnshi Alfred K, Kanmogne Georgette D

Abstract excerpt

In HIV-1 subtype-B, specific mutations in Gag cleavage sites (CS) are associated with treatment failure, with limited knowledge among non-B subtypes. We analyzed non-B HIV-1 gag and pol (protease/reverse-transcriptase) sequences from Cameroonians for drug resistance mutations (DRMs) in the gag P2/NC CS, and pol major DRMs. Phylogeny of the 141 sequences revealed a high genetic diversity (12 subtypes): 67.37%...

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Identifiers

PMID: 29074854
DOI: 10.1038/s41598-017-14095-4
PMCID: PMC5658410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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