Article
Natural polymorphism in protease and reverse transcriptase genes and in vitro antiretroviral drug susceptibilities of non-B HIV-1 strains from treatment-naive patients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2006
Vergne Laurence, Stuyver Lieven, Van Houtte Margriet, Butel Christelle, Delaporte Eric, Peeters Martine
Abstract excerpt
BACKGROUND: Most studies on antiretroviral (ARV) resistance of human immunodeficiency virus (HIV) have been done on subtype B which only represent a limited proportion of infections worldwide. OBJECTIVE: Understand baseline susceptibilities to ARVs in non-B strains. METHODS: To explore in greater detail possible intrinsic resistance to antiretroviral drugs in non-B subtypes, phenotypic resistance was tested in 35...
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