Article
Prevalence of drug resistance-related polymorphisms in treatment-naive individuals infected with nonsubtype B HIV type 1 in Cameroon.
AIDS research and human retroviruses - 1 Jul 2012
Youngpairoj Ae S, Alemnji George A, Eno Laura T, Lyonga Esther J, Eloundou Mbia A, Shanmugam Vedapuri, Mpoudi Eitel N, Folks Thomas M, Kalish Marcia L, Pieniazek Danuta, Fonjungo Peter N
Abstract excerpt
Mutations associated with the use of protease (PR) and reverse transcriptase (RT) inhibitors have been mostly mapped for HIV-1 subtype B. The prevalence of these mutations in drug-naive HIV-1 subtype B-infected individuals is low but occurs at high frequencies in treated individuals. To determine the prevalence of treatment-associated mutations in non-B viruses, we analyzed a 1613-bp pol region of specimens...
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