Article
Characterization of protease resistance-associated mutations in HIV type 1 drug-naive patients following the increasing prevalence of the CRF02_AG strain in Morocco.
AIDS research and human retroviruses - 1 Jun 2012
Miri Lamia, Ouladlahsen Ahd, Kettani Anass, Bensghir Rajaa, Marhoum Elfilali Kamal, Wakrim Lahcen
Abstract excerpt
The purpose of this study was to investigate the amino acid substitutions in the protease of HIV-1 B and non-B subtypes and evaluate whether the emergence of resistance-associated mutations (RAMs) could have a significant correlation with the increasing prevalence of CRF02_AG strains in Morocco. A total of 162 protease gene sequences were successfully amplified from drug-naive HIV-1-infected individuals. We...
Topics
- Adolescent
- Adult
- Algorithms
- Drug Resistance, Viral
- Female
- HIV Protease Inhibitors
- HIV Seropositivity
- HIV-1
- Humans
- Male
- Middle Aged