Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 Gag gene mutations, treatment response and drug resistance to protease inhibitors: A systematic review and meta-analysis protocol.

PloS one - 1 Jan 2021

Nka Alex Durand, Teto Georges, Santoro Maria Mercedes, Ngum Ndze Valantine, Takou Désiré, Dambaya Beatrice, Ngoufack Jagni Semengue Ezechiel, Fabeni Lavinia, Perno Carlo-Federico, Colizzi Vittorio, Ceccherini-Silberstein Francesca, Fokam Joseph

Abstract excerpt

BACKGROUND: Some mutations in the HIV-1 Gag gene are known to confer resistance to ritonavir-boosted protease inhibitors (PI/r), but their clinical implications remain controversial. This review aims at summarizing current knowledge on HIV-1 Gag gene mutations that are selected under PI/r pressure and their distribution according to viral subtypes. MATERIALS AND METHODS: Randomized and non-randomized trials,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Viral
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to HIV Protease Inhibitors

Share to Meta-Analysis as Topic

Share to Mutation

Share to Protein Precursors

Share to Systematic Reviews as Topic

Source

Open in PubMed Open full text

Identifiers

PMID: 34197501
DOI: 10.1371/journal.pone.0253587
PMCID: PMC8248685

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 Gag gene mutations, treatment response and drug resistance to protease inhibitors: A systematic review and meta-analysis protocol.PMID 34197501Read ↗

Hiv-1 Gag Gene Mutations, Treatment Response and Drug Resistance to Protease Inhibitors: A Systematic Review and Meta-analysis ProtocolSemantic proximity Read ↗

Navigating HIV-1 drug resistance: A comprehensive review of protease inhibitor efficacy and mutation dynamics.Semantic proximity Read ↗

A Surveillance on Protease Inhibitor Resistance-Associated Mutations Among Iranian HIV-1 PatientsSemantic proximity Read ↗

HIV-1 Drug Resistance Profiles for the HIV Protease and Reverse Transcriptase Gene in Patients Receiving Combination Therapy in Tehran, Iran.Semantic proximity Read ↗

Effect of human immunodeficiency virus type 1 protease inhibitor therapy and subtype on development of resistance in subtypes B and G.Semantic proximity Read ↗

Detection of Gag C-terminal mutations among HIV-1 non-B subtypes in a subset of Cameroonian patients.Semantic proximity Read ↗

Comparative analysis of drug resistance mutations in the human immunodeficiency virus reverse transcriptase gene in patients who are non-responsive, responsive and naive to antiretroviral therapy.Semantic proximity Read ↗

Protease inhibitor resistance update: where are we now?Semantic proximity Read ↗

Spectrum of Atazanavir-Selected Protease Inhibitor-Resistance MutationsSemantic proximity Read ↗

Determining and overcoming resistance to HIV protease inhibitors.Semantic proximity Read ↗

Integrative Computational Approaches for Understanding Drug Resistance in HIV-1 Protease Subtype CSemantic proximity Read ↗

[HIV resistance in men who have sex with men: a Meta-analysis].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.