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Article

RNF43 as a predictor of malignant transformation of pancreatic mucinous cystic neoplasm.

Virchows Archiv : an international journal of pathology - 1 Jun 2022

Sakihama Kukiko, Koga Yutaka, Yamamoto Takeo, Shimada Yuki, Yamada Yutaka, Kawata Jun, Shindo Koji, Nakamura Masafumi, Oda Yoshinao

Abstract excerpt

Mucinous cystic neoplasm (MCN) of the pancreas rarely progresses to invasive carcinoma, but few studies have analyzed genomic alterations involved in its malignant transformation. The relationships of ring finger protein 43 (RNF43) mutations with cytological atypia, RNF43 protein expression, and Wnt signaling proteins in MCN remain unclear. This study included 106 MCN cases, classified into 89 low-grade dysplasia...

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Identifiers

PMID: 35066614
DOI: 10.1007/s00428-022-03277-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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