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Article

Relevance of gene mutations and methylation to the growth of pancreatic intraductal papillary mucinous neoplasms based on pyrosequencing.

Scientific reports - 10 Jan 2022

Asano Go, Miyabe Katsuyuki, Kato Hiroyuki, Yoshida Michihiro, Sawada Takeshi, Okamoto Yasuyuki, Sahashi Hidenori, Atsuta Naoki, Kachi Kenta, Kato Akihisa, Jinno Naruomi, Natsume Makoto, Hori Yasuki, Naitoh Itaru, Hayashi Kazuki, Matsuo Yoichi, Takahashi Satoru, Suzuki Hiromu, Kataoka Hiromi

Abstract excerpt

We aimed to assess some of the potential genetic pathways for cancer development from non-malignant intraductal papillary mucinous neoplasm (IPMN) by evaluating genetic mutations and methylation. In total, 46 dissected regions in 33 IPMN cases were analyzed and compared between malignant-potential and benign cases, or between malignant-potential and benign tissue dissected regions including low-grade IPMN...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35013462
DOI: 10.1038/s41598-021-04335-z
PMCID: PMC8748617

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