Article
Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.
The Journal of pathology - 1 Jul 2014
Amato Eliana, Molin Marco Dal, Mafficini Andrea, Yu Jun, Malleo Giuseppe, Rusev Borislav, Fassan Matteo, Antonello Davide, Sadakari Yoshihiko, Castelli Paola, Zamboni Giuseppe, Maitra Anirban, Salvia Roberto, Hruban Ralph H, Bassi Claudio, Capelli Paola, Lawlor Rita T, Goggins Michael, Scarpa Aldo
Abstract excerpt
Intraductal neoplasms are important precursors to invasive pancreatic cancer and provide an opportunity to detect and treat pancreatic neoplasia before an invasive carcinoma develops. The diagnostic evaluation of these lesions is challenging, as diagnostic imaging and cytological sampling do not provide accurate information on lesion classification, the grade of dysplasia or the presence of invasion. Moreover,...
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