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Article

Molecular biomarkers for progression of intraductal papillary mucinous neoplasm of the pancreas.

Pancreas - 1 Mar 2015

Kuboki Yuko, Shimizu Kyoko, Hatori Takashi, Yamamoto Masakazu, Shibata Noriyuki, Shiratori Keiko, Furukawa Toru

Abstract excerpt

OBJECTIVES: We aimed to identify molecular biomarkers for assessing the progression of intraductal papillary mucinous neoplasm of the pancreas (IPMN). METHODS: We retrospectively investigated molecular aberrations and their associations with clinicopathological features in 172 IPMNs. RESULTS: GNAS and KRAS mutations were detected in 48% and 56% of IPMNs, respectively. No mutations of EGFR, PIK3CA GNAO1, GNAQ, or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinases

Share to Neoplasm Recurrence, Local

Share to Neoplasms, Cystic, Mucinous, and Serous

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Source

Identifiers

PMID: 25423558
DOI: 10.1097/MPA.0000000000000253

Genes

SMAD4
KRAS
EGFR
GNAS
GNAI2
GNAO1
GNAQ

Provenance

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