Article
SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells.
International journal of molecular sciences - 14 Jan 2022
Riccioni Veronica, Trionfetti Flavia, Montaldo Claudia, Garbo Sabrina, Marocco Francesco, Battistelli Cecilia, Marchetti Alessandra, Strippoli Raffaele, Amicone Laura, Cicchini Carla, Tripodi Marco
Abstract excerpt
Heterogeneous nuclear ribonucleoproteins (hnRNPs) control gene expression by acting at multiple levels and are often deregulated in epithelial tumors; however, their roles in the fine regulation of cellular reprogramming, specifically in epithelial-mesenchymal transition (EMT), remain largely unknown. Here, we focused on the hnRNP-Q (also known as SYNCRIP), showing by molecular analysis that in hepatocytes it...
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