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Hepatocyte nuclear factor 4α and cancer-related cell signaling pathways: a promising insight into cancer treatment

1 Jan 2021

Abstract excerpt

Hepatocyte nuclear factor 4α (HNF4α), a member of the nuclear receptor superfamily, is described as a protein that binds to the promoters of specific genes. It controls the expression of functional genes and is also involved in the regulation of numerous cellular processes. A large number of studies have demonstrated that HNF4α is involved in many human malignancies. Abnormal expression of HNF4α is emerging as a...

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PMID: 33462379
DOI: 10.1038/s12276-020-00551-1

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