Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuropilin-2 induced by transforming growth factor-β augments migration of hepatocellular carcinoma cells.

BMC cancer - 16 Nov 2015

Wittmann Philipp, Grubinger Markus, Gröger Christian, Huber Heidemarie, Sieghart Wolfgang, Peck-Radosavljevic Markus, Mikulits Wolfgang

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the third most lethal cancer worldwide. The epithelial to mesenchymal transition (EMT) describes the transformation of well-differentiated epithelial cells to a de-differentiated phenotype and plays a central role in the invasion and intrahepatic metastasis of HCC cells. Modulation of the transforming growth factor-β (TGF-β)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Liver Neoplasms

Share to Sulfhydryl Reagents

Share to Tissue Array Analysis

Share to Transforming Growth Factor beta

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 26573807
DOI: 10.1186/s12885-015-1919-0
PMCID: PMC4647494

Genes

NRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuropilin-2 induced by transforming growth factor-β augments migration of hepatocellular carcinoma cells.PMID 26573807Read ↗

The neuropilin 2 isoform NRP2b uniquely supports TGFβ-mediated progression in lung cancerSemantic proximity Read ↗

PDLIM2 prevents the malignant phenotype of hepatocellular carcinoma cells by negatively regulating β-catenin.Semantic proximity Read ↗

Neuropilins: expression and roles in the epitheliumSemantic proximity Read ↗

Neuropilins and liverSemantic proximity Read ↗

NANOG promotes liver cancer cell invasion by inducing epithelial–mesenchymal transition through NODAL/SMAD3 signaling pathwaySemantic proximity Read ↗

E2F1 promotes LIHC malignant phenotype via NEK2-mediated Wnt/β-catenin and Notch activation and EMT.Semantic proximity Read ↗

IGFBP2 drives epithelial-mesenchymal transition in Hepatocellular carcinoma via activating the Wnt/β-catenin pathwaySemantic proximity Read ↗

Neuropilin-1 upholds dedifferentiation and propagation phenotypes of renal cell carcinoma cells by activating Akt and sonic hedgehog axes.Semantic proximity Read ↗

Neuropilins: A New Target for Cancer TherapySemantic proximity Read ↗

Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancerSemantic proximity Read ↗

Genetic status of KRAS influences Transforming Growth Factor-beta (TGF-β) signaling: An insight into Neuropilin-1 (NRP1) mediated tumorigenesis.Semantic proximity Read ↗

MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.