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Clinical Significance and Regulation of ERK5 Expression and Function in Cancer

11 Jan 2022

Abstract excerpt

Extracellular signal-regulated kinase 5 (ERK5) is a unique kinase among MAPKs family members, given its large structure characterized by the presence of a unique C-terminal domain. Despite increasing data demonstrating the relevance of the ERK5 pathway in the growth, survival, and differentiation of normal cells, ERK5 has recently attracted the attention of several research groups given its relevance in...

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PMID: 35053510
DOI: 10.3390/cancers14020348

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