Article

The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival

2022-05-31

Abstract excerpt

Endometrial cancer (EC) is the most common type of gynaecologic cancer in women of developed countries. Despite surgery combined with chemo-/radiotherapy regimens, overall survival of patients with high-risk EC tumors is poor, indicating a need for novel molecular therapies. The MEK5-ERK5 pathway is activated in response to growth factors and to different forms of stress, including oxidative stress and cytokines....

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Literature Corpus work: b480edd8-8fe3-590f-ae16-d61716d77ab2
DOI: 10.1101/2022.05.31.494135

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