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E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and function

6 Mar 2023

Abstract excerpt

E26 transformation-specific (ETS) transcription variant 5 (ETV5), also known as ETS-related molecule (ERM), exerts versatile functions in normal physiological processes, including branching morphogenesis, neural system development, fertility, embryonic development, immune regulation, and cell metabolism. In addition, ETV5 is repeatedly found to be overexpressed in multiple malignant tumors, where it is involved...

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PMID: 36872348
DOI: 10.1186/s12929-023-00909-3

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