Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting the role of KLF5: from tumor progression to immune interactions with emphasis on glioma and bladder cancer.

Frontiers in immunology - 1 Jan 2025

Yuan Ze, Situ Minyi, Ye Yimeng, Zhang Jinhui, Jiang Kuntai, Zhang Shingyik, Deng Xinpei, He Zhenqiang, Luo Juncheng, Wang Yanjun

Abstract excerpt

Background: Krüppel-like factor 5 (KLF5) is involved in various aspects of tumor development, metastasis, and drug resistance through their regulation of transcription and translation, yet its functions in a comprehensive cancer framework are still unclear. Methods: Our research involved a detailed pan-cancer analysis using multi-omics data sourced from various public databases. We investigated the clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

Share to Glioma

Share to Kruppel-Like Transcription Factors

Share to Tumor Microenvironment

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 41583492
DOI: 10.3389/fimmu.2025.1730356
PMCID: PMC12823895

Genes

KLF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting the role of KLF5: from tumor progression to immune interactions with emphasis on glioma and bladder cancer.PMID 41583492Read ↗

Prognostic Significance and Immunological Role of FBXO5 in Human Cancers: A Systematic Pan-Cancer AnalysisSemantic proximity Read ↗

Gene expression profiling, prognosis, and immune microenvironment of KLF4 in malignanciesSemantic proximity Read ↗

The associations of SNF5 with prognosis and immune responses in bladder cancerSemantic proximity Read ↗

CCL5 might be a prognostic biomarker and associated with immuno-therapeutic efficacy in cancers: A pan-cancer analysisSemantic proximity Read ↗

Prognostic and Therapeutic Value of LSM5 Gene in Human Brain Cancer Glioma: An Omics Database Exploration ApproachSemantic proximity Read ↗

A Pan-Cancer Analysis of SLC12A5 Reveals Its Correlations with Tumor Immunity.Semantic proximity Read ↗

Prognostic value and drug sensitivity of FBXL6 in gliomaSemantic proximity Read ↗

FABP5 enhances malignancies of lower-grade gliomas via canonical activation of NF-κB signalingSemantic proximity Read ↗

Diagnostic significance and carcinogenic mechanism of pan-cancer gene POU5F1 in liver hepatocellular carcinomaSemantic proximity Read ↗

FABP5 enhances malignancies of lower‐grade gliomas via canonical activation of NF‐κB signalingSemantic proximity Read ↗

Role of interferon regulatory factor 5 (IRF5) in tumor progression: Prognostic and therapeutic potentialSemantic proximity Read ↗

Construction of a Novel T Cell Subtype with Immunotherapeutic Value in Bladder Cancer and a Neural Network-Based Prognostic ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.