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Article

Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases.

International journal of molecular sciences - 25 Sept 2022

Kim Uijin, Shin Ha Youn

Abstract excerpt

Signal transducer and activation of transcription 5 (STAT5) is a key transcription factor that regulates various biological processes in mammalian development. Aberrant regulation of STAT5 has also been causally linked to many diseases, including cancers and immune-related diseases. Although persistent activation of STAT5 due to dysregulation of the signaling cascade has been reported to be associated with the...

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Identifiers

PMID: 36232600
DOI: 10.3390/ijms231911297
PMCID: PMC9569778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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