Article
Lipid-Associated Variants near ANGPTL3 and LPL Show Parent-of-Origin Specific Effects on Blood Lipid Levels and Obesity.
Genes - 29 Dec 2021
Lessmark Anna, Hatem Gad, Kovacs Györgyi, Vitai Marta, Ahlqvist Emma, Tuomi Tiinamaija, Koranyi Laszlo, Groop Leif, Prasad Rashmi B
Abstract excerpt
Parent-of-origin effects (POE) and sex-specific parental effects have been reported for plasma lipid levels, and a strong relationship exists between dyslipidemia and obesity. We aim to explore whether genetic variants previously reported to have an association to lipid traits also show POE on blood lipid levels and obesity. Families from the Botnia cohort and the Hungarian Transdanubian Biobank (HTB) were...
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