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Article

Associations between common genetic polymorphisms in angiopoietin-like proteins 3 and 4 and lipid metabolism and adiposity in European adolescents and adults.

The Journal of clinical endocrinology and metabolism - 1 Dec 2009

Legry Vanessa, Bokor Szilvia, Cottel Dominique, Beghin Laurent, Catasta Giovina, Nagy Eniko, Gonzalez-Gross Marcela, Spinneker Andre, Stehle Peter, Molnár Dénes, Moreno Luis A, Amouyel Philippe, Dallongeville Jean, Meirhaeghe Aline

Abstract excerpt

CONTEXT: Plasma-borne angiopoietin-like proteins (ANGPTL) act as endocrine factors on their target tissues. Because ANGPTL3 and ANGPTL4 play important roles in lipid metabolism and the regulation of adiposity in mice, we hypothesized that genetic variability at the ANGPTL3 and ANGPTL4 genes loci might influence lipid metabolism and fat deposition in humans. OBJECTIVE: The aim of the study was to examine the...

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Source

Identifiers

PMID: 19890028
DOI: 10.1210/jc.2009-0769

Genes

ANGPTL3
ANGPTL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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