Article
Sex-Specific Parental Effects on Offspring Lipid Levels.
Journal of the American Heart Association - 30 Jun 2015
Predazzi Irene M, Sobota Rafal S, Sanna Serena, Bush William S, Bartlett Jacquelaine, Lilley Jessica S, Linton MacRae F, Schlessinger David, Cucca Francesco, Fazio Sergio, Williams Scott M
Abstract excerpt
BACKGROUND: Plasma lipid levels are highly heritable traits, but known genetic loci can only explain a small portion of their heritability. METHODS AND RESULTS: In this study, we analyzed the role of parental levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TGs) in explaining the values of the corresponding traits in...
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