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Article

Proteomimetics of Natural Regulators of JAK–STAT Pathway: Novel Therapeutic Perspectives

3 Jan 2022

Abstract excerpt

The JAK-STAT pathway is a crucial cellular signaling cascade, including an intricate network of Protein-protein interactions (PPIs) responsible for its regulation. It mediates the activities of several cytokines, interferons, and growth factors and transduces extracellular signals into transcriptional programs to regulate cell growth and differentiation. It is essential for the development and function of both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35047557
DOI: 10.3389/fmolb.2021.792546

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