The Sperm Protein Spaca6 is Essential for Fertilization in Zebrafish

doi:10.3389/fcell.2021.806982

Article

The Sperm Protein Spaca6 is Essential for Fertilization in Zebrafish

3 Jan 2022

Abstract excerpt

Fertilization is a key process in all sexually reproducing species, yet the molecular mechanisms that underlie this event remain unclear. To date, only a few proteins have been shown to be essential for sperm-egg binding and fusion in mice, and only some are conserved across vertebrates. One of these conserved, testis-expressed factors is SPACA6, yet its function has not been investigated outside of mammals. Here...

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