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Article

spe-12 encodes a sperm cell surface protein that promotes spermiogenesis in Caenorhabditis elegans.

Genetics - 1 May 1999

Nance J, Minniti A N, Sadler C, Ward S

Abstract excerpt

During spermiogenesis, Caenorhabditis elegans spermatids activate and mature into crawling spermatozoa without synthesizing new proteins. Mutations in the spe-12 gene block spermatid activation, rendering normally self-fertile hermaphrodites sterile. Mutant males, however, are fertile. Surprisingly, when mutant hermaphrodites mate with a male, their self-spermatids activate and form functional spermatozoa,...

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Source

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Identifiers

PMID: 10224255
DOI: 10.1093/genetics/152.1.209
PMCID: PMC1460590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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