Article
Role of monogenic diabetes genes on beta cell function in Italian patients with newly diagnosed type 2 diabetes. The Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 13.
Diabetes & metabolism - 1 Jul 2022
Bonetti S, Zusi C, Rinaldi E, Boselli M L, Csermely A, Malerba G, Trabetti E, Bonora E, Bonadonna R C, Trombetta M
Abstract excerpt
We tested the hypothesis that common genetic variability of beta-cell genes responsible for monogenic diabetes may affect beta cell function in type 2 diabetes mellitus (T2DM). We studied 794 drug- naïve GAD-negative patients with newly diagnosed T2DM (age: median=59 years; I.Q. range: 52-66; body mass index: 29.3 kg/m2; 26.6-32.9). Beta-cell function was assessed by state-of-art mathematical modeling of...
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