Article
High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients.
Diabetologia - 1 Jun 2014
Gjesing Anette P, Hornbak Malene, Allin Kristine H, Ekstrøm Claus T, Urhammer Søren A, Eiberg Hans, Pedersen Oluf, Hansen Torben
Abstract excerpt
AIMS/HYPOTHESIS: The aim of this study was to estimate the heritability of quantitative measures of glucose regulation obtained from a tolbutamide-modified frequently sampled IVGTT (t-FSIGT) and to correlate the heritability of the glucose-stimulated beta cell response to the tolbutamide-induced...
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