ScalpelSig Designs Targeted Genomic Panels from Data to Detect Activity of Mutational Signatures.

Abstract excerpt

Over the past decade, a promising line of cancer research has utilized machine learning to mine statistical patterns of mutations in cancer genomes for information. Recent work shows that these statistical patterns, commonly referred to as "mutational signatures," have diverse therapeutic potential as biomarkers for cancer therapies. However, translating this potential into reality is hindered by limited access...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Breast Neoplasms