Article
Cancer mutational signatures representation by large-scale context embedding.
Bioinformatics (Oxford, England) - 1 Jul 2020
Zhang Yang, Xiao Yunxuan, Yang Muyu, Ma Jian
Abstract excerpt
MOTIVATION: The accumulation of somatic mutations plays critical roles in cancer development and progression. However, the global patterns of somatic mutations, especially non-coding mutations, and their roles in defining molecular subtypes of cancer have not been well characterized due to the computational challenges in analysing the complex mutational patterns. RESULTS: Here, we develop a new algorithm, called...
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