Article
Genetic diversity in enhancer II region of HBV genotype D and its association with advanced liver diseases.
PloS one - 1 Jan 2000
Khan Majid, Khan Sanaullah, Gondal Mehrunnisa Fatima, Bibi Safia, Khan Bakht Tarin, Majid Abdul, Khattak Ayesha, Khabir Muhammad Nasir, Anwar Muhammad, Gul Aisha, Naseem Maryam, Attaullah Sobia
Abstract excerpt
BACKGROUND: Hepatitis B Virus (HBV) is one of the most common human infectious agents, and the mutations in its genome may cause chronic hepatitis (CH), liver cirrhosis (LC), and hepatocellular carcinoma (HCC). This study was designed to characterize the enhancer-II (Enh-II) region of X gene in HBV positive patients to assess the association of such mutations with CH, LC, and HCC. METHODS: HBV positive samples (N...
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