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Article

Targeted deep sequencing reveals APC mutations as predictors of overall survival in Chinese colorectal patients receiving adjuvant chemotherapy.

Scandinavian journal of gastroenterology - 1 Apr 2022

Chen Xin, Hu Mengjun, Chen Ying, Li Ajian, Hua Yutong, Jiang Huihong, Li Huaguang, Lin Moubin

Abstract excerpt

Objective: Targeted deep sequencing was used to characterize the mutational spectrum of APC in Chinese colorectal tumors in comparison to that in Caucasians from The Cancer Genome Atlas (TCGA) and to investigate whether APC mutations can predict overall survival in CRC patients receiving adjuvant chemotherapy.Methods: A total of 315 Chinese CRC patients including 241 stage II/III patients receiving...

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Identifiers

PMID: 34978498
DOI: 10.1080/00365521.2021.2022189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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