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Article

Prognostic significance of interaction between somatic APC mutations and 5-fluorouracil adjuvant chemotherapy in Taiwanese colorectal cancer subjects.

American journal of clinical oncology - 1 Apr 2009

Chen Shee-Ping, Wu Chang-Chieh, Lin Shinn-Zong, Kang Jung-Cheng, Su Chin-Cheng, Chen Yi-Lin, Lin Po-Cheng, Chiu Sheng-Chun, Pang Cheng-Yoong, Harn Horng-Jyh

Abstract excerpt

OBJECTIVE: The correlations between adenomatous polyposis coli (APC) mutations and 5-fluorouracil (5-FU) adjuvant chemotherapy and colorectal cancer (CRC) patients' prognosis are not well known. We performed an exploratory study to investigate the association between APC mutations and the survival of Taiwanese CRC subjects who received 5-FU adjuvant chemotherapy. METHODS: Full-length APC gene isolated from tumor...

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Share to Antimetabolites, Antineoplastic
Share to Chemotherapy, Adjuvant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

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Source

Identifiers

PMID: 19307944
DOI: 10.1097/COC.0b013e318181f959

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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