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Article

Enhancing the landscape of colorectal cancer using targeted deep sequencing.

Scientific reports - 14 Apr 2021

Lee Chul Seung, Song In Hye, Lee Ahwon, Kang Jun, Lee Yoon Suk, Lee In Kyu, Song Young Soo, Lee Sung Hak

Abstract excerpt

Targeted next-generation sequencing (NGS) technology detects specific mutations that can provide treatment opportunities for colorectal cancer (CRC) patients. We included 145 CRC patients who underwent surgery. We analyzed the mutation frequencies of common actionable genes and their association with clinicopathological characteristics and oncologic outcomes using targeted NGS. Approximately 97.9% (142) of...

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Identifiers

PMID: 33854094
DOI: 10.1038/s41598-021-87486-3
PMCID: PMC8046812

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