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Identification of APC Mutation as a Potential Predictor for Immunotherapy in Colorectal Cancer

13 Jul 2022

Abstract excerpt

To date, anticancer immunotherapy has presented some clinical benefits to most of advanced mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) colorectal cancer (CRC) patients. In addition to MSI status, we aimed to reveal the potential predictive value of adenomatous polyposis coli (APC) gene mutations in CRC patients. A total of 238 Chinese CRC patients was retrospectively identified and...

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PMID: 35874638
DOI: 10.1155/2022/6567998

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