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Gene mutation profiling in Chinese colorectal cancer patients and its association with clinicopathological characteristics and prognosis.

Cancer medicine - 1 Jan 2020

Ye Zu-Lu, Qiu Miao-Zhen, Tang Tao, Wang Fang, Zhou Yi-Xin, Lei Meng-Jie, Guan Wen-Long, He Cai-Yun

Abstract excerpt

BACKGROUND: Gene mutations may play an important role in the development, response to treatment and prognosis of colorectal cancer (CRC). This retrospective study aimed to investigate the mutation profiling of Chinese patients with CRC, and its correlation with clinicopathological features and prognosis. METHODS: This study included 1190 Chinese CRC patients who were diagnosed between May 1998 and December 2018...

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Identifiers

PMID: 31782259
DOI: 10.1002/cam4.2727
PMCID: PMC6970031

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