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Article

Comprehensive functional genomic analyses link APC somatic mutation and mRNA-miRNA networks to the clinical outcome of stage-III colorectal cancer patients.

Biomedical journal - 1 Apr 2022

Chiang Sum-Fu, Huang Heng-Hsuan, Tsai Wen-Sy, Chin-Ming Tan Bertrand, Yang Chia-Yu, Huang Po-Jung, Yi-Feng Chang Ian, Lin Jiarong, Lu Pei-Shan, Chin En, Liu Yu-Hao, Yu Jau-Song, Chiang Jy-Ming, Hung Hsin-Yuan, You Jeng-Fu, Liu Hsuan

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is a major health concern globally, but exhibits regional and/or environmental distinctions in terms of outcome especially for patients with stage III CRC. METHODS: From 2014 to 2016, matched pairs of tumor and adjacent normal tissue samples from 60 patients with stage I-IV CRC from Chang Gung Memorial Hospital in Taiwan were analyzed using next-generation sequencing. The DNA,...

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Share to Adenomatous Polyposis Coli
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35550340
DOI: 10.1016/j.bj.2021.03.001
PMCID: PMC9250073

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