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Article

Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene.

The Journal of allergy and clinical immunology - 1 Jun 2022

Kan Mengyuan, Diwadkar Avantika R, Shuai Haoyue, Joo Jaehyun, Wang Alberta L, Ong Mei-Sing, Sordillo Joanne E, Iribarren Carlos, Lu Meng X, Hernandez-Pacheco Natalia, Perez-Garcia Javier, Gorenjak Mario, Potočnik Uroš, Burchard Esteban G, Pino-Yanes Maria, Wu Ann Chen, Himes Blanca E

Abstract excerpt

BACKGROUND: Inhaled corticosteroid (ICS) response among patients with asthma is influenced by genetics, but biologically actionable insights based on associations have not been found. Various glucocorticoid response omics data sets are available to interrogate their biological effects. OBJECTIVE: We sought to identify functionally relevant ICS-response genetic associations by integrating complementary multiomics...

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Share to Adrenal Cortex Hormones
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34971648
DOI: 10.1016/j.jaci.2021.11.025
PMCID: PMC9177524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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