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Article

GSDMB/ORMDL3 Rare/Common Variants Are Associated with Inhaled Corticosteroid Response among Children with Asthma.

Genes - 28 Mar 2024

Voorhies Kirsten, Mohammed Akram, Chinthala Lokesh, Kong Sek Won, Lee In-Hee, Kho Alvin T, McGeachie Michael, Mandl Kenneth D, Raby Benjamin, Hayes Melanie, Davis Robert L, Wu Ann Chen, Lutz Sharon M

Abstract excerpt

Inhaled corticosteroids (ICS) are efficacious in the treatment of asthma, which affects more than 300 million people in the world. While genome-wide association studies have identified genes involved in differential treatment responses to ICS in asthma, few studies have evaluated the effects of combined rare and common variants on ICS response among children with asthma. Among children with asthma treated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38674355
DOI: 10.3390/genes15040420
PMCID: PMC11049905

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