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Article

Electron cryo-tomography structure of axonemal doublet microtubule from Tetrahymena thermophila.

Life science alliance - 1 Mar 2022

Li Sam, Fernandez Jose-Jesus, Fabritius Amy S, Agard David A, Winey Mark

Abstract excerpt

Doublet microtubules (DMTs) provide a scaffold for axoneme assembly in motile cilia. Aside from α/β tubulins, the DMT comprises a large number of non-tubulin proteins in the luminal wall of DMTs, collectively named the microtubule inner proteins (MIPs). We used cryoET to study axoneme DMT isolated from Tetrahymena We present the structures of DMT at nanometer and sub-nanometer resolution. The structures confirm...

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Identifiers

PMID: 34969817
DOI: 10.26508/lsa.202101225
PMCID: PMC8742875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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