Article

Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1

2024-12-04

Abstract excerpt

Motile cilia are unique organelles with the ability to autonomously move. Force generated by beating cilia propels cells and moves fluids. The ciliary skeleton is made of peripheral doublet microtubules and a central pair (CP) with a distinct structure at the tip. In this study, we present a high-resolution structure of the CP in the ciliary tip of the ciliate Tetrahymena thermophila and identify several tip prot...

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Literature Corpus work: 6d6106fc-a7a4-57e6-9124-f6fbbad0a049
DOI: 10.1101/2024.12.02.626492

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