Article

CryoEM structure of the <i>Trypanosoma brucei</i> flagellum central apparatus

2025-05-30

Abstract excerpt

Axonemes are cylindrical bundles of microtubule filaments that typically follow a 9+n pattern (where n ranges from 0 to 4). However, variations exist across species and cell types, including architectures with fewer (e.g., 3+0, 6+0) or more than nine doublet microtubules (e.g., 9+9+0, 9+9+3), reflecting diverse structural adaptations of cilia and flagella in eukaryotes. Trypanosoma brucei , the causative agent o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b9fb277e-8cc1-53bd-a6f5-08776181fad3
DOI: 10.1101/2025.05.29.656921

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CryoEM structure of the <i>Trypanosoma brucei</i> flagellum central apparatusDOI 10.1101/2025.05.29.656921Read

Evolutionary adaptations of doublet microtubules in trypanosomatid parasitesSemantic proximity Read

Trypanosome doublet microtubule structures reveal flagellum assembly and motility mechanismsSemantic proximity Read

Three-Dimensional Structure of the Trypanosome Flagellum Suggests that the Paraflagellar Rod Functions as a Biomechanical SpringSemantic proximity Read

Structural and Functional Insights into the Microtubule Organizing Centers of <em>Toxoplasma gondii</em> and <em>Plasmodium spp</em>.Semantic proximity Read

FAP20 is required for flagellum assembly in <i>Trypanosoma brucei</i>Semantic proximity Read

Cryo-electron tomography of periplasmic flagella in Borrelia burgdorferi reveals a distinct cytoplasmic ATPase complexSemantic proximity Read

Electron cryo-tomography structure of axonemal doublet microtubule from Tetrahymena thermophila.Semantic proximity Read

Variable microtubule architecture in the malaria parasiteSemantic proximity Read

In situ structures of periplasmic flagella reveal a distinct cytoplasmic ATPase complex in <i>Borrelia burgdorferi</i>Semantic proximity Read

Molecular architecture of the sheathed polar flagellum in <i>Vibrio alginolyticus</i>Semantic proximity Read

Atypical flagella assembly and haploid genome coiling during male gamete formation in PlasmodiumSemantic proximity Read

The Cytoskeleton of Trypanosomatid ParasitesSemantic proximity Read