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Human MSC-Derived Exosomes Reduce Cellular Senescence in Renal Epithelial Cells

17 Dec 2021

Abstract excerpt

Cellular senescence of renal tubular cells is associated with chronic diseases and age-related kidney disorders. Therapies to antagonize senescence are, therefore, explored as novel approaches in nephropathy. Exosomes derived from human mesenchymal stroma-/stem-like cells (MSC) entail the transfer of multiple bioactive molecules, exhibiting profound regenerative potential in various tissues, including therapeutic...

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PMID: 34948355
DOI: 10.3390/ijms222413562

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