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Cellular senescence in the aging and diseased kidney

19 Dec 2017

Abstract excerpt

The program of cellular senescence is involved in both the G1 and G2 phase of the cell cycle, limiting G1/S and G2/M progression respectively, and resulting in prolonged cell cycle arrest. Cellular senescence is involved in normal wound healing. However, multiple organs display increased senescent cell numbers both during natural aging and after injury, suggesting that senescent cells can have beneficial as well...

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Share to Epigenetics and DNA Methylation
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PMID: 29260442
DOI: 10.1007/s12079-017-0434-2

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