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Cellular senescence of renal tubular epithelial cells in acute kidney injury

5 Feb 2024

Abstract excerpt

Cellular senescence represents an irreversible state of cell-cycle arrest during which cells secrete senescence-associated secretory phenotypes, including inflammatory factors and chemokines. Additionally, these cells exhibit an apoptotic resistance phenotype. Cellular senescence serves a pivotal role not only in embryonic development, tissue regeneration, and tumor suppression but also in the pathogenesis of...

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PMID: 38316761
DOI: 10.1038/s41420-024-01831-9

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