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Targeting cellular senescence in kidney diseases and aging: A focus on mesenchymal stem cells and their paracrine factors

18 Dec 2024

Abstract excerpt

Cellular senescence is a phenomenon distinguished by the halting of cellular division, typically triggered by DNA injury or numerous stress-inducing factors. Cellular senescence is implicated in various pathological and physiological processes and is a hallmark of aging. The presence of accumulated senescent cells, whether transiently (acute senescence) or persistently (chronic senescence) plays a dual role in...

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PMID: 39696575
DOI: 10.1186/s12964-024-01968-1

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