Article
Protein-Bound Uremic Toxins in Senescence and Kidney Fibrosis
2023-08-09
Abstract excerpt
Chronic kidney disease (CKD) is a progressive condition of kidney dysfunction due to diverse causes of injury. In healthy kidneys, protein-bound uremic toxins (PBUTs) are cleared from the systemic circulation by proximal tubule cells through the concerted action of plasma membrane transporters that facilitate their urinary excretion, but the endogenous metabolites are hardly removed with kidney dysfunction and may...
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Identifiers and source
- Literature Corpus work
- 7984cee6-be91-55f8-b624-fa2a8860a139
- DOI
- 10.20944/preprints202308.0733.v1